smiFISH - single molecule inexpensive fluorescence in situ hybridisation

A set consisting of short, target-binding, unlabelled oligo probes (OligoPool) and a double-labelled secondary probe allows extremely sensitive and specific in situ RNA detection.



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Take advantage of state-of-the-art synthesis technology:
Oligonucleotides with all popular modifications at reasonable prices and with a reliable quality. Oligos for PCR, short, unmodified and quickly delivered are offered as well as high quality RNA oligos, probes for qPCR and FISH or reliable cloning oligos of (nearly) any length.
Talking about oligonucleotides:
talk to biomers.net!

Oligo products:
- Random Hexamer
- Oligo dT20
- Universal Reporter
- RNase Substrate,...
qPCR Mastermix
Chemicals for oligonucleotide synthesis

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Distearoyl lipid-oligonucleotide conjugates

- similar to the natural phospholipid structure
- increase of cell permeability
- binding of oligonucleotides to the cell surface



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Our biomers.net quencher set nearly covers the complete wavelength range of visible light:

BMN-Q460 (400-530 nm), BMN-Q535 (480-580 nm), BMN-Q590 (550-650 nm), BMN-Q620 (480-720 nm) and BMN-Q650 (550-720 nm)

biomers.net dyes: BMN-488, BMN-505, BMN-536, BMN-562

Protein tags such as SNAP or CLIP tag as well as HaloTag® but also the sortase-mediated linking reaction are used in various applications:

- detection
- localisation
- protein-protein interactions
- labelling, multiplex labelling (e.g. SNAP / CLIP tag)
- enzymatic coupling of different proteins or other biomolecules

Between 6:00 and 9:30 am you‘ll get a special discount of
5 % on all your orders!

Protocols, interesting literature and further information around the topic of oligonucleotides.

- Smart-Seq for transkriptome analysis (Picelli et al., 2014)
- Mediator Probe PCR (Faltin et al., 2012)
- MiL-FISH: Multi-labelled oligonucleotides (Schimak et al., 2015)