Christmas holidays

We are closed during the holidays from 23. Dec. 2024 until 01. Jan. 2025. We will be back at your service on the 02. Jan. 2025! The last shipment before the holidays will leave us in the afternoon of 20. Dec. 2024. Please make sure that the delivery can be accepted at your place. We wish you a Merry Christmas and a Happy New Year.

RNase substrate

Sensitive substrate for quick detection of RNases starting at 98€

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pH Indicator on the oligo

Carboxy-SNARF as a
5'-/3'-modification on the oligo enables pH-dependent color change.
Contact us for further information.
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Maleimide oligos

stable and covalent coupling with thiols
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Triglycine/Sortase

Sortase-mediated coupling reaction via triglycine-modified oligos

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XXL DNA

DNA oligo amounts from 10 to 500 mg, HPLC purification incl. [Read more]

New: Reactive modifiers

Reactive dyes and modifiers for postynthetic labeling of oligonucleotides: azide, alkyne, succinimidyl ester modifiers.
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Pseudouridine

Pseudouridine and N1-Methyl-Pseudouridine modified oligonucleotides.
Please contact us!
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Carbohydrate oligonucleotide conjugates
 

Carbohydrate oligonucleotide conjugates

Carbohydrate oligonucleotide conjugates 


Carbohydrate-oligonucleotide conjugates have become increasingly important in recent years, particularly with regard to an increased uptake and cell availability of siRNA and antisense oligonucleotides. Of particular interest here is N-acetylgalactosamine (GalNAc), which can bind to the asialoglycoprotein receptor (ASGPR) in hepatocytes.

The following picture shows some examples of the attachment of carbohydrates (sugars) to oligonucleotides via different linker structures:

  • N-Acetyl-Galactosamin (GalNAc)
  • ß-Cyclodextrin
  • Glucopyranose

 

If you need further information, please contact our customer support team at any time.
We look forward to assist you in realising your personal project. 
Tel +49 731 70 396 0   ǀ   info@biomers.net