Oligos, DNA / RNA Synthesis - biomers.net Oligonucleotides

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Between 8 am and 7 pm for all and any questions around your oligonucleotides call:

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+49 731 70396 0

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+49 731 70396 11

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info@biomers.net

We help you with everything around oligonucleotides - fast, competently and reliably!

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RNase substrate

Sensitive substrate for quick detection of RNases starting at 98€

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pH Indicator on the oligo

Carboxy-SNARF as a
5'-/3'-modification on the oligo enables pH-dependent color change.
Contact us for further information.
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Maleimide oligos

stable and covalent coupling with thiols
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Triglycine/Sortase

Sortase-mediated coupling reaction via triglycine-modified oligos

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XXL DNA

DNA oligo amounts from 10 to 500 mg, HPLC purification incl. [Read more]

New: Reactive modifiers

Reactive dyes and modifiers for postynthetic labeling of oligonucleotides: azide, alkyne, succinimidyl ester modifiers.
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Pseudouridine

Pseudouridine and N1-Methyl-Pseudouridine modified oligonucleotides.
Please contact us!
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YOUR TRUSTED PARTNER FOR OLIGONUCLEOTIDES:
FAST, COMPETENT, AND RELIABLE!

Take advantage of state-of-the-art synthesis technology:
Oligonucleotides with all popular modifications at reasonable prices and with a reliable quality. Oligos for PCR, short, unmodified and quickly delivered are offered as well as high quality RNA oligos, probes for qPCR and FISH or reliable cloning oligos of (nearly) any length.
Talking about oligonucleotides:
talk to biomers.net!

Mid Scale synthesis (XXL DNA)

XXL DNA
For DNA oligonucleotide amounts from 10 to 500 mg
HPLC purification is included.
For further information please contact our customer support service at any time!

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Maleimide-modified oligos

Maleimide-modified oligos easily react with thiol forming a
stable covalent bond between the corresponding molecules.

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Modifications for enzymatic coupling of oligonucleotides to proteins

HaloTag®

Benzylguanine und Benzylcytosine

Triglycin (Gly-Gly-Gly) for sortase-mediated linking reaction

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5'-Hydrazide Modification: Reactive Linker

An efficient way to link oligos to other biomolecules is the hydrazide-aldehyde coupling.
Aldehydes represent highly reactive carbonyl compounds that can react with hydrazides under neutral or slightly acidic conditions to form stable hydrazone conjugates in a fast and efficient way. Thus, a conjugation of oligonucleotides to other (bio)molecules can be achieved easily under physiological conditions.

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Lipophilic modifications

Lipophilic modifications on oligos play an important role in drug delivery and nanobiotechnology.

Cholesterol
Conjugates with palmitic-, stearic-, elaidic-, oleic acid
Distearoyl-Lipid
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamin (DOPE) conjugate
Tocopherol (Vitamine E), Trolox, Folic acid conjugate

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Early Bird Discount

Between 6:00 and 9:30 am you‘ll get a special discount of
5 % on all your orders!

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DNA oligos

- Unmodified oligos
- short and extra long oligos
- XXL DNA (10-500 mg)
- Sequence modifications
- Wobbles

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RNA oligos

- unmodified RNA
up to 120 bases
- RNA oligo annealing
- XL and XXL RNA (5-50 mg)
- RNA modifications
- 2´-modified RNA

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qPCR Probes

- Dual-Labelled Oligos
- Double Quenched Probes
- MGB Probes
- Molecular Beacons
- Scorpions
- FRET Probes

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PNA oligos

- Peptide nucleic acid oligomers (PNA)
- 6-25 bases
- various modifications possible
- extreme stability

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FISH Probes

- Fluorescence probes
mono-, dope-, tetraProbes
- multiProbes
- HRP probes
- smiFISH Oligo Pools

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Literature Highlight

- Rapid SARS-CoV-2 detection with RT-RPA and RT-LAMP
- Gly-Gly-Gly-modified oligonucleotides
- L-DNA oligonucleotides for DNA-PAINT

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