News Highlights with biomers.net 

- new Abberior dyes for fluorescence microscopy applications as 5'- and 3'-modifications in the portfolio:
Abberior STAR 460L
Abberior STAR GREEN
Abberior STAR ORANGE
Abberior STAR RED
Abberior STAR deepRED

- new BMN dyes from biomers.net:
BMN-550 (identical to Atto 550)
BMN-Rho11 (idental to Atto Rho11)

- new redox modifcation for electrochemical detection:
5‘-Neutral Red ACH (c)
Oligonucleotide-based electrochemical biosensors (E-sensors) for the sensitive and selective detection of specific DNA sequences (e.g. SNP detection). Further information on oligonucleotides with redox-active reporter molecules (e.g. methylene blue, ferrocene, anthraquinone, viologen, Nile Blue, Atto MB2) can be found here. 

- Copper-chelating azide modifications:
Azid (Bis-Triazol Azid) (5'-Modifikation)
Azid (Bis-Triazol Azid) Ser (3'-Modifikation)
Chelating azides with an additional ligand function that stabilizes the copper(I) center after binding to the azide, thereby efficiently activating the azide and accelerating the click reaction. In addition, chelating azides allow the use of reduced amounts of the cytotoxic copper catalyst, thereby minimizing heavy metal residues in the final product. 

- 5'-Pomalidomide-PEG3 (ACH, c) and 5'-Thalidomide-PEG2 (ACH, c)
Immunomodulatory modifications that are applied to the 5'-end of the oligonucleotide via copper-catalyzed click chemistry. 

- 5'-DOPE ACH (c) and 5'-DSPE ACH (c) with lipophilic character
Coupling of the phospholipids to the 5'-end of the oligo via click chemistry.

- Literature highlights 
 

Experienced and highly skilled synthesis specialists in production, along with an in-house research laboratory, enable the continuous improvement of established processes. The development of new nucleic acid synthesis and modification techniques allows us to address your individual needs and implement customer-oriented, complex synthesis strategies.
We are constantly expanding our range of modifications to offer you the best possible results for your research.

Simply contact us at +49 731 70 396 0 or info@biomers.net if you have any questions or would like further information about our products.