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Dinitrophenol (DNP) (5' modification)
The small molecule dinitrophenol has been established for long as a label in immunohistochemistry and immunocytochemistry. Dinitrophenol is also used to label oligonucleotide probes, in particular for the use in in-situ hybridisation (ISH or multicolor FISH).
Dinitrophenol can be coupled via an amino linker or a TEG linker to the oligonucleotide.
![Dinitrophenol (DNP) 5' modification: 5´-Dinitrophenol (DNP)](/en/Catalog/Modifications/Images/DNPSE/MOD5/DNPSE_MOD5_112943502-350x350.png)
5´-Dinitrophenol (DNP)